Wednesday, June 8, 2011

Neuronascent, Inc

I hadn't heard of this until it came across one of the Down syndrome lists I'm on. It'll be curious to see what this neurogenesis program involves.

CLARKSVILLE, MD--(Marketwire - Jun 2, 2011) - Neuronascent, Inc. announced today that the Company has received funding from both the federal government, under the Qualifying Therapeutic Discovery Project for the development of its preclinical therapeutic candidates for neurodegenerative diseases, and from Maryland's Biotechnology Center, to accelerate development of its neurogenic candidate for Down syndrome. The latter project is a collaboration with Dr. Barbara Slusher, Chief Scientific Officer, Johns Hopkins University's NeuroTranslational Brain Center.

Neuronascent aims to develop non-invasive therapeutics for central nervous system indications with high unmet need. The company's lead compounds, currently in preclinical testing, are developed to regenerate neurons and provide specialized neuroprotection for newly generated and surviving neurons under neurodegenerative diseases. These potentially disease-modifying effects aim to improve behavioral outcomes including motor function and memory. Animal studies with these compounds have previously shown a reversal of cognitive loss in aged mice to young levels.

"These funds will allow us to provide proof-of-principle that our neurogenic therapeutic may be effective for Down syndrome, a new target for drug development," said Judith Kelleher-Andersson, Ph.D., President and Chief Scientific Officer. "These funds also afford us the opportunity to pursue multiple preclinical studies to further develop our lead agents for clinical trials in Alzheimer's and Parkinson's disease."

Founded in 2004 by Dr. Kelleher-Andersson, Neuronascent, Inc. is a small-molecule central nervous system drug discovery company, developing novel therapeutics using their neurogenesis discovery platform. Neuronascent has laboratories in Rockville and Frederick, Maryland.

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